Thelisemia and its treatment

Hello Dr. Rizwan

i hope you will be fine. I would like to be discussed a very serious desease that is called thelisemia.

kindly tell me what is thelisemia?

how many kinds of thelisemia are?

and what is the cure of this desease?

and is it an expensive desease to be treated?

kindly do answer all my questions in detail.

it will be so kind of you............

thelisimia

Drs and experts.......

plz replyyyyyyyy

ji janab Thalassemia

Dr John Hatherley

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re: thalasemia

re: kindly tell me what is thelisemia?

yeh aik khoon ki bemari hai, yeh aik genetic beemari hai

re: how many kinds of thelisemia are?

generally ye do qisim ke hote hai major aur minor

re: and what is the cure of this desease?

yeh bemari cure nahi hoti, is mai musalsal khoon lena perta hai

re: and is it an expensive desease to be treated?

yes expansive tu hai, lekin Pakistan mai kai rafahee adare free mai bhi blood transfuse ker dete hai

re: kindly do answer all my questions in detail.

detail jawab dena mushkil hai, aap apne patient ki tafseel bataye tu os ke mutabiq koi proper jawab dia jaaye ga.

minor thalasimia

Assalamoalaikum

hmare family mai kisi ko thalasimia nhi hai mgr ab pta chla k meri sister nd baaki khandan walo ko minor thalasimia hai jo fore fatherz se inherit hoa hai hme bones mai pain hota hai mujy bi yhi prb hai mgr test nhi krwaya k hai ya nhi mgr jo symptoms bakio ko hai wo mujy bi hai mgr i feel pain in my all bones boht tests krwaye sb normal thy bs ye test nhi krwaya

re...beta thal minor

beta thalessemia minor is actually not that uncommon as it is supposed to be (overall 6% in pakistan population exclusive of families with cousin marriages,much high in them).... but the person who has minor thalessemia is only anemic(decreased Hb level) no other major symptoms occur but what precaution to be taken is that do not marry a male person with beta thalassemia minor as otherwise in each child risk of having major thalssemia is upto 25percent....

this is of type of anemia that does not require iron supplementation as body is already absorbing from gut.in excess....(if not associated with superadded iron defeciency anemia)

.and thales major patnt have excess iron load in body,.plus if we start from basic the tests required are

haemoglobin level

peripheral blood smear

reticulocyte count

hematocrit%(PCV)

RBC indices(MCV,MCH,MCHC)

HB electrophoresis(bit expensive but diagnostic)

iron level in serum,serum ferritin and total iron binding capacity...

to waterr

thank u vv much for ue reply .

meri sistr ko minor thalasimia hai or hmare skin anamic hai jb b doctor k pas gye skin anamic lik k dya . ap btaye kia mujy bi minor thalsimia hai kio k iron ki kmi nd bones mai pain to hota hi hai mujy nd meri ek or sistr ko thora sa kaam krte hai to thk jatye hai .

mujy konse tests krwane prengy k mai apni ek o4r sistr ka bi kroo or apna test bi kroo k hmy tho nhi

ok....

yes ap ke har sibbling mai chance he 50percent thalessemia minor ka...

blood ke test hotey han ye jo maine likhe han

haemoglobin level

peripheral blood smear

reticulocyte count

hematocrit%(PCV)

RBC indices(MCV,MCH,MCHC)

HB electrophoresis(bit expensive but diagnostic)

iron level in serum,serum ferritin and total iron binding capacity

ye app karwa lain if u want to confirm inn par ho jata he..

baqe bone marrow ke test ya genetic wo apko agar doc kahein...unke filhal zaroort nai..ok

but the person who has minor thalessemia is only anemic(decreased Hb level) no other major symptoms occur but what precaution to be taken is that do not marry a male person with beta thalassemia minor as otherwise in each child risk of having major thalssemia is upto 25percent....

waterr

re

maine bataya na unke her baby ke waqat 25percent chance hoga ke shaid wo baby thal major ho...

there is a diagnostic test done these days called as choriovillous sampling  and also amniotic fluid analysis(for karotyping) it is done at around 8week of pregnancy...it can be found by taking placenta tissue and fluid in sac k baby ya fetus thalassemia major tu nai he...agar ho tu iss par  saudia ke ulma ka fatwa he k pregnancy can be aborted before 11week of pregnancy mai ye nai keh rai ke wo abortion karwain but just telling facts...........plus the child itself isnt in good shape meaning by prone to infections,spleen n liver enlarge massively,easy bleeding,less life span...

the hospt which is with my medical institute has biggest thalassemia center in lahore....i tell u they give blood almost free to the poor thal major babies but still medicines ka kharcha per year one and half  lac he...

i am not horrifying u..

only 25percent chance he in each baby to be thal major... n thats the trouble...thal minor nahe

bone marrow transplant is the option not only difficult to find a match but also really expensive waisey family mai match mil he jata he

salam saira

saira khan ap b apna test kurwaa lyn water ny kaf i tufseel ap ko dee hy es  bary meh.ye murz kafi poranaa hy lykin es py kam 1925 meh shoro howa sub sy ziada ye murz itly or es k puroos k momaalik meh hy,

thalassaa younaani naam hy jis ka mtlab somandar hy or aemia k mani blood k hen, west meh ye murz ziyada ta lykin waha pree mariage counciling or Genetic counciling ki kamyaabi ki waja sy thalasimia py kaboo pa leya ghiyaa.

pakistan meh ghaoo dyhaato meh thalasimia ka shaahoor or ni hy or close family  or czn marrages ziyaaa hony ki waja sy waa ziyada hy,

es leye ap ko b muswara hy k close family or czn marrage sy purhyz kurin.

 thalassameia major k buchy tu moshkil sy dus saal tuk jee paty hen,jub k thalassameia minor ka murz es bat py monhasar kurta hy k kis age meh zahaer hoti hy,5 sy 6 saal ki age meh zaher ho tu moshkil sy he juwaani ko ponchty hen. thalassamia major k mureezo k leye blood is life

thalasimia k mureez man and woman ko apus meh hurgez shadi ni kurni chaieye, ir czn mrg sy b purhyz ,

Blood Haemoglobin tes hur three months bhad kurwana chaiye or LFT liver function test hur 6 month bahd  hur saal pots medical test.

eski treatment meh boon marrow transplant hy pur bahot expencive hy  pur  ye 7 sal sy 13 saal tuk k lyee hy. es ka khurch 12 sy 14 lak hy. or kamyaabi k chancs 60% sy 70 %.

more

thalassaemia minor children meh hota hy yani essy buchy jin k parants meh dono meh sy ek meh thalassaemia k genes hoty hen.thalassaemia minor k mureez rozana k mamoolaat zindgi meh etny motaasir ni hoty laykin thalassaemia minor ki women mureezo meh during pragnency blood ki kumi hoti hy,jis ko folic acid ki ek tab rozana sy poraa keya ja sukta hy,

thalassaemia major

ye bemaari shudeed kisam ki hy esy bucho k parants k father mother dono meh es k genes hoty hen es k mureezo ko khas tuwja ki or elaaj ki zroorat hoti hy,enka sari life jub tuk jety hen blood kaaym hoti hy en mureezo ko hur month blood ki zroorat hoti hy,or es k sath frritin test ye test iron load sy buchny k leye hur 6 month bahd krwana chaiye narmal quantity 250/ng per ml sy kum hoti hy,

ye mikdaar 1000lng mer ml sy b hur jay tu disferal inj lazmi ho jata hy lugana.

baki hematologists sy  bakayda treatment kurwani chaiye

thank u all

mtlb